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Computational Biology: Dr Sue Jones

Contact Details

Senior Lecturer Room 3B6 JMS Building
Department of Chemistry & Biochemistry
University of Sussex
Falmer, BN1 9QG

s.jones"at"sussex.ac.uk

Grants

  • Medical Research Council: 2005-2008 (200K GBP)
    Functional Genomics: computational prediction of RNA-binding function from sequence.
  • Royal Society: 2003-2004 (15K GBP)
    Computational prediction of RNA-binding function from protein structure.

Publications

2009

  • RNA-binding residues in sequence space: conservation and interaction patterns.
    Spriggs RV & Jones S. (2009)
    Computational Biology and Chemistry. In press.
  • Protein function annotation from sequence: prediction of residues interacting with RNA.
    Spriggs RV, Murakami Y, Nakamura H & Jones S. (2009)
    Bioinformatics 25 p25 p1492-1497.
  • ProtorP: A protein-protein interaction analysis server.
    Reynolds C, Damerell D & Jones S. (2009)
    Bioinformatics. 25 p413-414.

    2008

  • Evaluating conformational changes in protein structures binding RNA
    Ellis J.J & Jones S. (2008)
    Proteins: Structure, Function and Bioinformatics 70 p1518-26.

  • Computational and Structural Characterisation of Protein Associations
    Jones S. (2008)
    in Protein Dimerization (and oligomerization) in Biology. Editor J. Matthews. Landes BioScience

    2007

  • Protein-RNA Interactions: structural analysis and functional classes
    Ellis J.J, Broom M. & Jones S. (2007)
    Proteins: Structure, Function and Bioinformatics 66 p903-911. PDF

  • Patch prediction of protein interaction sites: validation of a scoring function for an online server
    Jones S & Murakami Y. (2007)
    Lecture Notes in Bioinformatics LNBI 4414 p303-113 PDF
    2006

  • SHARP2: protein-protein interaction predictions using patch analysis
    Murakami Y & Jones S. (2006)
    Bioinformatics 22 p1794-1795 PDF

    2005

  • HTHquery: a method for detecting DNA-binding proteins with a helix-turn-helix structural motif.
    Ferrer-Costa C, Shanahan, HP, Jones S & Thornton JM. (2005)
    Bioinformatics 21 p3679-3680.

    2004

  • Identifying DNA binding proteins using structural motifs and the electrostatic potential
    Shanahan HP. Garcia MA, Jones S & Thornton JM (2004)
    Nucleic Acids Research 32 p4732-4741

  • An overview of basic helix-loop-helix proteins
    Jones S (2004)
    Genome Biology 5:226

  • Determination of protein charge by capillary zone electrophoresis
    Winzor DJ, Jones S & Harding SE (2004)
    Analytical Biochemistry 333 p225-229

  • Searching for functional sites in protein structures
    Jones S & Thornton JM (2004)
    Current Opinion in Chemical Biology 8 p3-7

    2003

  • Using electrostatic potentials to predict DNA-binding sites on DNA-binding proteins
    Jones S, Shanahan H, Berman HM & Thornton JM (2003)
    Nucleic Acids Research 31 p7189-7198

  • Using structural motifs to identify proteins with DNA binding function.
    Jones S, Barker J, Nobeli I & Thornton JM (2003)
    Nucleic Acids Research 31 p2811-2823

  • Protein-DNA interactions: the story so far and a new method for prediction
    Jones S & Thornton JM (2003)
    Comparative and Functional Genomics 4 p428-431

    2001

  • The cohesin complex: sequence homologies, interaction networks and shared motifs
    Jones S & Sgouros J. (2001)
    Genome Biology 2 (3) 0009

  • Protein-RNA interactions: a structural analysis
    Jones S, Daley DTA, Luscombe NM, Berman HM & Thornton JM. (2001)
    Nucleic Acids Research 29 p943-954

    2000

  • Protein Domain Interfaces: characterisation and comparison with oligomeric protein interfaces
    Jones S, Marin A, & Thornton JM. (2000)
    Protein Engineering 13 p77-82

  • Analysis and prediction of carbohydrate binding sites
    Taroni C, Jones S, & Thornton JM. (2000)
    Protein Engineering 13 p89-98

    1999

  • Novel Size-Independent Modeling of the Dilute Solution Conformation of the Immunoglobulin IgG Fab' domain using SOLPRO and ELLIPS
    Carrasco B, Garcia de la Torre J, Byron O, King D, Walters C, Jones S & Harding SE. (1999)
    Biophysical Journal 77 p2902-2910

  • COVOL: An interactive program for evaluating second virial coefficients from the triaxial shape or dimensions of rigid macromolecules.
    Harding SE, Horton JC, Jones S, Thornton JM & Winzor DJ. (1999)
    Biophysical Journal 76 p2432-2438.

  • Protein-DNA Interactions: A Structural Analysis
    Jones, S, van Heyningen P, Berman HM, Thornton, JM. (1999)
    Journal of Molecular Biology 287 p877-896

    1998

  • Protein domains, folds and functions.
    Jones S, Martin ACR, Karmirantzou M, Laskowski RA, Orengo CA, Thornton JM (1998)
    Transactions, American Crystallographic Association, Annual Meeting 1997.

  • Classifying a Protein in the CATH Database of Domain Structures
    Orengo, CA, Martin, AM, Hutchinson, EG, Jones, S, Jones, DT, Michie, AD, Swindells, MB, Thornton, JM (1998)
    Acta Cryst D54 p1155-1167

  • New Tools and Resources for Analysing Protein Structures and Their Interactions
    Luscombe, NM, Laskowski, RA, Westhead, DR, Milburn, D, Jones, S, Karmirantzou M, Thornton, JM. (1998)
    Acta Cryst D54 p1132-1138.

  • Protein Folds and Function
    Martin, ACR, Orengo, CA, Hutchinson, EG, Jones, S, Laskowski, RA, Mitchell, JBO, Taroni, C, Thornton, JM (1998)
    Structure, 1998, Vol 6. p.875-884.

  • Domain Assignment for Protein Structures using a Consensus Approach: Characterisation and Analysis
    Jones, S., Stewart, M., Michie, A., Swindells, M., Orengo, C., Thornton, J. (1998)
    Protein Science Vol 7. p.233-242.

    1997

  • CATH- A Hierarchic Classification of Protein Domain Structures
    Orengo, C., Michie, A., Jones, S., Jones, D., Swindells, M., and Thornton, J. (1997)
    Structure. Vol 5. No 8. p.1093-1108

  • Prediction of Protein-Protein Interaction Sites Using Patch Analysis
    Jones, S. and Thornton, J.M. (1997)
    Journal of Molecular Biology. Vol 272 p133-143.

  • Analysis of Protein-Protein Interaction Sites Using Surface Patches
    Jones, S. and and Thornton, J.M. (1997)
    Journal of Molecular Biology. Vol 272 p121-132.

    1996

  • Principles of Protein-Protein Interactions Derived From Structural Studies
    Jones, S. and Thornton, J.M. (1996)
    Proceedings of The National Academy of Science (U.S.A). Vol. 93 p.13-20.

    1995

  • Protein-Protein Interactions: A Review of Protein Dimer Structures
    Jones, S. and Thornton, J.M. (1995)
    In Progress in Biophysics and Molecular Biology: Vol 63 p31-165.

    Updated 21/08/09
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